Bacterial Cell Wall and Glycobiology         (AG Prof. Dr. Christoph Mayer)


Research in my group is located in the intercept between chemistry and biology.

Our major goal is to understand bacteria at the molecular level and our research currently focuses on bacterial cell wall physiology and amino sugar metabolism:

  • Elucidation of cell wall recycling and amino sugar catabolic pathways
  • Identification of novel enzymes acting on peptidoglycan
  • Structure and mechanism of enzymes involved in the bacterial cell wall recycling
  • Protein engineering and directed evolution of protein function

    Some of our current projects are: 
  • Cell wall recycling metabolism in Gram-negative (E. coli, Pseudomonas sp.) and Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus)  
  • Cell lysis and consumption during cannibalistic growth of Bacillus subtilis
  • Cell wall metabolism of the oral pathogen Tannerella forsythia
  • Structure and mechanism of MurNAc-6P etherase and MurNAc-1P uridylyl transferase          
  • WTA catabolism

    More infos to our research projects




Our research is currently funded
by the DFG,
the GRK1708,
and the SFB766
LINK to the SFB766 homepage

LINK to the GRK1708 homepage


Prof. Dr. Christoph Mayer

University of Tübingen

Auf der Morgenstelle 28

72076 Tübingen


Dep. of Microbiology & Biotechnology


Room E9 P32

+49 (7071) 29-74645



Mr. & Ms. Hottmann
Congratulations to your marriage!


12. May, 2015:

Publication in Nature Communications
collaboration with researchers at the DSMZ
Press release


26. January, 2014: Publication in Nature
collaboration with researchers at the Univ. of Konstanz
Press release

30. June, 2013: Publication in Nature Chem. Biol.

Press release

Project funded by a Dr. Marietta-Lutze-stipend by the Dr. Kade Pharma 
and the Konstanz Graduate School-Chemical Biology